One analysis of research included 12 studies in people who took ashwagandha doses between 120 mg and 1,250 mg per day. People have used ashwagandha for thousands of years to relieve stress, increase energy levels, and improve concentration. This medication may affect blood sugar levels. Certain conditions are well known to decrease testosterone in men, including excess fat, especially around the abdomen, which interferes with hormone signals from the brain to the testicle, experts say. The study highlights the need for men already on testosterone therapies to closely monitor their levels after starting weight loss medications, Portillo said. A testosterone test is the only way to know for sure if you have low testosterone levels. You can test your testosterone levels with a testosterone test. In those cases, testosterone testing can help diagnose conditions like polycystic ovary syndrome, or PCOS, adrenal disorders or rare tumors. "In general, we don’t routinely measure testosterone in women, unless there are signs of a hormonal imbalance, like excess facial hair (hirsutism), irregular periods, infertility or signs of masculinization," Portillo said. Testosterone tends to decline gradually with age, starting around the late 30s to early 40s. The study shows the dual benefit of weight loss medications in men, said Dr. Fatima Cody Stanford, obesity medicine physician scientist at Massachusetts General Hospital and Harvard Medical School. It's important to talk to your health care professional about your own blood glucose levels and if you’re at risk for going low. Part of living with diabetes is fluctuations in your blood glucose levels. Initial research suggests that fenugreek can boost testosterone levels and sexual function in males. While a small, annual decline in testosterone levels is a normal part of the aging process, you can take action to optimize your levels and avoid symptoms of low testosterone. Even if you don’t have any symptoms of low testosterone, it’s still good to get a blood test annually, she says. There are also many ways you can naturally boost testosterone levels, but those should be done in conjunction with TRT. If you are experiencing any symptoms as described above, you should definitely get your hormone levels checked. When your testosterone levels are getting into the 1,000 up to the 1,500 ng/dL range—and staying up there—that’s too high, says McDevitt. "Testosterone has a mood stabilizing effect, so as it decreases, anxiety can arise." There are a couple of science-backed ways to help you boost testosterone levels naturally. Even if your total testosterone levels are in a normal range, your free testosterone can still be low. This is often caused by high blood glucose levels or stress. Low testosterone and high blood glucose can cause erectile dysfunction. Adiposity even lessens the sex hormone-binding globulin, which transmits testosterone in the blood. The excess abdominal fat further reduces testosterone production and increases that of estradiol—a female reproductive hormone—in men. Conversely, men also need to maintain healthy body fat distribution to regulate this hormone. When there is insulin resistance in the body, the pancreas tries to work harder to ensure adequate insulin production. This treatment is legal in Australia and is offered by specialised hormone therapy clinics such as TRT Australia, but it is heavily regulated, and patients must both present with symptoms and speak to a licensed healthcare professional before beginning treatment. For example, a study in 50 adults ages 65–80 found that taking 600 mg of ashwagandha root per day for 12 weeks significantly improved sleep quality and mental alertness upon waking compared with a placebo treatment. The reason may be that certain compounds within ashwagandha — including one called withaferin A (WA) — have powerful antidiabetic activity and may help stimulate cells to take in glucose from the bloodstream. Ashwagandha may help increase testosterone levels and may have some potential benefits for male fertility. Additionally, a review of four studies found that ashwagandha treatment significantly increased sperm concentration, semen volume, and sperm motility in males with low sperm count. The limited research available suggests that ashwagandha may help reduce symptoms of depression and benefit people with some mental health conditions. Some evidence suggests that ashwagandha may help reduce symptoms of other mental health conditions, including depression, in certain populations. At this time there are no age-specific testosterone reference ranges for males or females. These simple blood tests can be administered by a medical professional in a lab or through an at-home testosterone test kit. Your doctor can help confirm the results, or they may order additional tests to understand what factors could be causing your low or high hormone levels. If you took an at-home testosterone level test and your results showed levels outside the standard range, it may be worthwhile to make an appointment to see a doctor to discuss the results. Regular exercise reduces your risk of an abundance of health conditions and diseases. Just a small drop in testosterone can have a huge impact on how you feel. The hard truth about testosterone and erectile dysfunction He has advised on the development and governance of health technologies, with a particular focus on evidence-based care, patient safety, and medical communication. Dr Luke Pratsides is a General Practitioner working in the NHS, with a background in clinical leadership across digital health.